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İstanbul has been a cultural hub and the capital of three major empires: Roman, Byzantine, and Ottoman. Emperor Constantine made it the Roman Empire's capital in 330 AD due to its strategic location, renaming it Constantinople. During Byzantine rule, the city expanded with new walls and iconic structures like Hagia Sophia. Despite challenges, such as the Crusaders’ plunder and the Latin rule, it regained prominence before the Ottoman conquest in 1453 by Mehmet the Conqueror.
Under Ottoman rule, Istanbul flourished as a center of culture, science, and art, with domes and minarets reshaping its skyline. The city endured events like the 1509 earthquake and entered the 16th century as one of the world's largest cities. It became a global capital during Suleiman the Magnificent's reign and the center of the Islamic world under the Ottomans.
The Tulip Era (1718–1730) marked modernization efforts, and constitutional reforms brought administrative changes in the late 19th and early 20th centuries. Occupied after World War I, Istanbul was liberated in 1923 but lost its capital status when the Republic of Turkey was founded with Ankara as the capital. Despite this, Istanbul remains historically and culturally significant as a city that bridged civilizations and eras.